Repurposing hyperpolarization‐activated cyclic nucleotide‐gated channels as a novel therapy for breast cancer

Hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels are members of the voltage‐gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel‐blocker, is FDA‐approved for clinical use as a heart rate‐reducing agent....

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Detalles Bibliográficos
Autores principales: Mok, Ka‐Chun, Tsoi, Ho, Man, Ellen PS, Leung, Man‐Hong, Chau, Ka Man, Wong, Lai‐San, Chan, Wing‐Lok, Chan, Sum‐Yin, Luk, Mai‐Yee, Chan, Jessie Y.W., Leung, Jackie K.M., Chan, Yolanda H.Y., Batalha, Sellma, Lau, Virginia, Siu, David C.W., Lee, Terence K.W., Gong, Chun, Khoo, Ui‐Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567035/
https://www.ncbi.nlm.nih.gov/pubmed/34841695
http://dx.doi.org/10.1002/ctm2.578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567035/
https://www.ncbi.nlm.nih.gov/pubmed/34841695
http://dx.doi.org/10.1002/ctm2.578

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