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Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells

BACKGROUND: Lipid rafts (LRs), cholesterol‐enriched microdomains on cell membranes, are increasingly viewed as signalling platforms governing critical facets of cancer progression. The phenotype of cancer stem‐like cells (CSCs) presents significant hurdles for successful cancer treatment, and the ex...

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Detalles Bibliográficos
Autores principales: Park, So‐Yeon, Kim, Jee‐Heun, Choi, Jang‐Hyun, Lee, Choong‐Jae, Lee, Won‐Jae, Park, Sehoon, Park, Zee‐Yong, Baek, Jeong‐Heum, Nam, Jeong‐Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567043/
https://www.ncbi.nlm.nih.gov/pubmed/34841679
http://dx.doi.org/10.1002/ctm2.552