IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression

Background: Neuron apoptosis, regulated by endoplasmic reticulum (ER) stress in the hippocampus, is an essential factor influencing the cognitive impairment induced by hypobaric hypoxia. Hypoxia mainly changes the activating transcription factor (ATF6) pathway of ER stress. However, the role of ATF6...

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Detalles Bibliográficos
Autores principales: Zhou, Simin, Zhong, Zhifeng, Huang, Pei, Xiang, Bin, Li, Xiaoxu, Dong, Huaping, Zhang, Gang, Wu, Yu, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567049/
https://www.ncbi.nlm.nih.gov/pubmed/34744770
http://dx.doi.org/10.3389/fphys.2021.729925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567049/
https://www.ncbi.nlm.nih.gov/pubmed/34744770
http://dx.doi.org/10.3389/fphys.2021.729925

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