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IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression
Background: Neuron apoptosis, regulated by endoplasmic reticulum (ER) stress in the hippocampus, is an essential factor influencing the cognitive impairment induced by hypobaric hypoxia. Hypoxia mainly changes the activating transcription factor (ATF6) pathway of ER stress. However, the role of ATF6...
Autores principales: | Zhou, Simin, Zhong, Zhifeng, Huang, Pei, Xiang, Bin, Li, Xiaoxu, Dong, Huaping, Zhang, Gang, Wu, Yu, Li, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567049/ https://www.ncbi.nlm.nih.gov/pubmed/34744770 http://dx.doi.org/10.3389/fphys.2021.729925 |
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