Circadian Rhythm Disruption Influenced Hepatic Lipid Metabolism, Gut Microbiota and Promoted Cholesterol Gallstone Formation in Mice

BACKGROUND: Hepatic lipid metabolism regulates biliary composition and influences the formation of cholesterol gallstones. The genes Hmgcr and Cyp7a1, which encode key liver enzymes, are regulated by circadian rhythm-related transcription factors. We aimed to investigate the effect of circadian rhyt...

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Detalles Bibliográficos
Autores principales: He, Chuanqi, Shen, Weiyi, Chen, Chaobo, Wang, Qihan, Lu, Qifan, Shao, Wentao, Jiang, Zhaoyan, Hu, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567099/
https://www.ncbi.nlm.nih.gov/pubmed/34745000
http://dx.doi.org/10.3389/fendo.2021.723918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567099/
https://www.ncbi.nlm.nih.gov/pubmed/34745000
http://dx.doi.org/10.3389/fendo.2021.723918

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