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Block of Voltage-Gated Sodium Channels as a Potential Novel Anti-cancer Mechanism of TIC10

Background: Tumor therapeutics are aimed to affect tumor cells selectively while sparing healthy ones. For this purpose, a huge variety of different drugs are in use. Recently, also blockers of voltage-gated sodium channels (VGSCs) have been recognized to possess potentially beneficial effects in tu...

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Detalles Bibliográficos
Autores principales: Fuchs, Eva, Messerer, David Alexander Christian, Karpel-Massler, Georg, Fauler, Michael, Zimmer, Thomas, Jungwirth, Bettina, Föhr, Karl Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567104/
https://www.ncbi.nlm.nih.gov/pubmed/34744721
http://dx.doi.org/10.3389/fphar.2021.737637