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Assessment of the In Vitro and In Vivo Antifungal Activity of NSC319726 against Candida auris

Candida auris is an emerging yeast pathogen of candidemia with the ability to develop resistance to all current antifungal drug classes. Novel antifungal therapies against C. auris are warranted. NSC319726 is a thiosemicarbazone with an inhibitory effect on fungal ribosome biogenesis that has demons...

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Detalles Bibliográficos
Autores principales: Li, Jizhou, Coste, Alix T., Bachmann, Daniel, Sanglard, Dominique, Lamoth, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567239/
https://www.ncbi.nlm.nih.gov/pubmed/34730380
http://dx.doi.org/10.1128/Spectrum.01395-21