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Degradation of WTAP blocks antiviral responses by reducing the m(6)A levels of IRF3 and IFNAR1 mRNA

N (6)‐methyladenosine (m(6)A) is a chemical modification present in multiple RNA species and is most abundant in mRNAs. Studies on m(6)A reveal its comprehensive roles in almost every aspect of mRNA metabolism, as well as in a variety of physiological processes. Although some recent discoveries indi...

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Detalles Bibliográficos
Autores principales: Ge, Yong, Ling, Tao, Wang, Yao, Jia, Xin, Xie, Xiongmei, Chen, Rong, Chen, Shangwu, Yuan, Shaochun, Xu, Anlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567250/
https://www.ncbi.nlm.nih.gov/pubmed/34467630
http://dx.doi.org/10.15252/embr.202052101