Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

Although commonly associated with autophagosomes, LC3 can also be recruited to membranes by covalent lipidation in a variety of non-canonical contexts. These include responses to ionophores such as the M2 proton channel of influenza A virus. We report a subtractive CRISPR screen that identifies fact...

Descripción completa

Detalles Bibliográficos
Autores principales: Ulferts, Rachel, Marcassa, Elena, Timimi, Lewis, Lee, Liam Changwoo, Daley, Andrew, Montaner, Beatriz, Turner, Suzanne Dawn, Florey, Oliver, Baillie, John Kenneth, Beale, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567314/
https://www.ncbi.nlm.nih.gov/pubmed/34706226
http://dx.doi.org/10.1016/j.celrep.2021.109899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567314/
https://www.ncbi.nlm.nih.gov/pubmed/34706226
http://dx.doi.org/10.1016/j.celrep.2021.109899

Ejemplares similares