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Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery

After demyelinating injury of the central nervous system, resolution of the mounting acute inflammation is crucial for the initiation of a regenerative response. Here, we aim to identify fatty acids and lipid mediators that govern the balance of inflammatory reactions within demyelinating lesions. U...

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Detalles Bibliográficos
Autores principales: Penkert, Horst, Bertrand, Alix, Tiwari, Vini, Breimann, Stephan, Müller, Stephan A., Jordan, Paul M., Gerl, Mathias J., Klose, Christian, Cantuti-Castelvetri, Ludovico, Bosch-Queralt, Mar, Levental, Ilya, Lichtenthaler, Stefan F., Werz, Oliver, Simons, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567315/
https://www.ncbi.nlm.nih.gov/pubmed/34706241
http://dx.doi.org/10.1016/j.celrep.2021.109898