Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED

Conventional targeted sequencing methods eliminate many of the benefits of nanopore sequencing, such as the ability to accurately detect structural variants (SVs) or epigenetic modifications. The ReadUntil method allows nanopore devices to selectively eject reads from pores in real-time, which could...

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Detalles Bibliográficos
Autores principales: Kovaka, Sam, Fan, Yunfan, Ni, Bohan, Timp, Winston, Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567335/
https://www.ncbi.nlm.nih.gov/pubmed/33257863
http://dx.doi.org/10.1038/s41587-020-0731-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567335/
https://www.ncbi.nlm.nih.gov/pubmed/33257863
http://dx.doi.org/10.1038/s41587-020-0731-9

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