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Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED
Conventional targeted sequencing methods eliminate many of the benefits of nanopore sequencing, such as the ability to accurately detect structural variants (SVs) or epigenetic modifications. The ReadUntil method allows nanopore devices to selectively eject reads from pores in real-time, which could...
Autores principales: | Kovaka, Sam, Fan, Yunfan, Ni, Bohan, Timp, Winston, Schatz, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567335/ https://www.ncbi.nlm.nih.gov/pubmed/33257863 http://dx.doi.org/10.1038/s41587-020-0731-9 |
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