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Conformational selection of vasopressin upon V(1a) receptor binding

The neuropeptide vasopressin (VP) and its three G protein-coupled receptors (V(1a)R, V(1b)R and V(2)R) are of high interest in a wide array of drug discovery programs. V(1a)R is of particular importance due to its cardiovascular functions and diverse roles in the central nervous system. The structur...

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Detalles Bibliográficos
Autores principales: Che, Kateryna, Muttenthaler, Markus, Kurzbach, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567363/
https://www.ncbi.nlm.nih.gov/pubmed/34765097
http://dx.doi.org/10.1016/j.csbj.2021.10.024