Cargando…
Conformational selection of vasopressin upon V(1a) receptor binding
The neuropeptide vasopressin (VP) and its three G protein-coupled receptors (V(1a)R, V(1b)R and V(2)R) are of high interest in a wide array of drug discovery programs. V(1a)R is of particular importance due to its cardiovascular functions and diverse roles in the central nervous system. The structur...
Autores principales: | Che, Kateryna, Muttenthaler, Markus, Kurzbach, Dennis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567363/ https://www.ncbi.nlm.nih.gov/pubmed/34765097 http://dx.doi.org/10.1016/j.csbj.2021.10.024 |
Ejemplares similares
-
Photoswitchable
Probes of Oxytocin and Vasopressin
por: Wirth, Ulrike, et al.
Publicado: (2023) -
Toward protein NMR at physiological concentrations by hyperpolarized water—Finding and mapping uncharted conformational spaces
por: Epasto, Ludovica M., et al.
Publicado: (2022) -
Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin
por: Dekan, Zoltan, et al.
Publicado: (2021) -
I8-arachnotocin–an arthropod-derived G protein-biased ligand of the human vasopressin V(2) receptor
por: Duerrauer, Leopold, et al.
Publicado: (2019) -
In vitro binding and receptor-mediated activity of terlipressin at vasopressin receptors V(1) and V(2)
por: Jamil, Khurram, et al.
Publicado: (2017)