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miR-1307 promotes hepatocarcinogenesis by CALR-OSTC-endoplasmic reticulum protein folding pathway

miR-1307 is highly expressed in liver cancer and inhibits methyltransferase protein8. Thereby, miR-1307 inhibits the expression of KDM3A and KDM3B and increases the methylation modification of histone H3 lysine 9, which enhances the expression of endoplasmic-reticulum-related gene CALR. Of note, miR...

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Detalles Bibliográficos
Autores principales: Xie, Sijie, Jiang, Xiaoxue, Qin, Rushi, Song, Shuting, Lu, Yanan, Wang, Liyan, Chen, Yingjie, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567365/
https://www.ncbi.nlm.nih.gov/pubmed/34761190
http://dx.doi.org/10.1016/j.isci.2021.103271