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miR-1307 promotes hepatocarcinogenesis by CALR-OSTC-endoplasmic reticulum protein folding pathway
miR-1307 is highly expressed in liver cancer and inhibits methyltransferase protein8. Thereby, miR-1307 inhibits the expression of KDM3A and KDM3B and increases the methylation modification of histone H3 lysine 9, which enhances the expression of endoplasmic-reticulum-related gene CALR. Of note, miR...
Autores principales: | Xie, Sijie, Jiang, Xiaoxue, Qin, Rushi, Song, Shuting, Lu, Yanan, Wang, Liyan, Chen, Yingjie, Lu, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567365/ https://www.ncbi.nlm.nih.gov/pubmed/34761190 http://dx.doi.org/10.1016/j.isci.2021.103271 |
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