Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70

Merkel cell carcinoma is an aggressive skin malignancy, mostly caused by Merkel cell polyomavirus (MCPyV). MCPyV T-antigens can induce mature microRNA expressions through the DnaJ domain, but its underlying mechanism is still unknown. Here, we report that the T-antigens induce protein expression and...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Jiwei, Shi, Hao, Juhlin, C Christofer, Larsson, Catharina, Lui, Weng-Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567380/
https://www.ncbi.nlm.nih.gov/pubmed/34761184
http://dx.doi.org/10.1016/j.isci.2021.103264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567380/
https://www.ncbi.nlm.nih.gov/pubmed/34761184
http://dx.doi.org/10.1016/j.isci.2021.103264

Ejemplares similares