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Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes

Internalized and ubiquitinated signaling receptors are silenced by their intraluminal budding into multivesicular bodies aided by the endosomal sorting complexes required for transport (ESCRT) machinery. HD-PTP, an ESCRT protein, forms complexes with ESCRT-0, -I and -III proteins, and binds to Endof...

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Detalles Bibliográficos
Autores principales: Kazan, Jalal M., Desrochers, Guillaume, Martin, Claire E., Jeong, Hyeonju, Kharitidi, Dmitri, Apaja, Pirjo M., Roldan, Ariel, St. Denis, Nicole, Gingras, Anne-Claude, Lukacs, Gergely L., Pause, Arnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567383/
https://www.ncbi.nlm.nih.gov/pubmed/34761192
http://dx.doi.org/10.1016/j.isci.2021.103274