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Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation
Postsynaptic density protein 95 is a key scaffolding protein in the postsynaptic density of excitatory glutamatergic neurons, organizing signaling complexes primarily via its three PSD-95/Discs-large/Zona occludens domains. PSD-95 is regulated by phosphorylation, but technical challenges have limite...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567388/ https://www.ncbi.nlm.nih.gov/pubmed/34761188 http://dx.doi.org/10.1016/j.isci.2021.103268 |