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Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation

Postsynaptic density protein 95 is a key scaffolding protein in the postsynaptic density of excitatory glutamatergic neurons, organizing signaling complexes primarily via its three PSD-95/Discs-large/Zona occludens domains. PSD-95 is regulated by phosphorylation, but technical challenges have limite...

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Detalles Bibliográficos
Autores principales: Vistrup-Parry, Maria, Chen, Xudong, Johansen, Thea L., Bach, Sofie, Buch-Larsen, Sara C., Bartling, Christian R.O., Ma, Chenxue, Clemmensen, Louise S., Nielsen, Michael L., Zhang, Mingjie, Strømgaard, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567388/
https://www.ncbi.nlm.nih.gov/pubmed/34761188
http://dx.doi.org/10.1016/j.isci.2021.103268