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Impact of senescence on the transdifferentiation process of human hepatic progenitor-like cells

BACKGROUND: Senescence is characterized by a decline in hepatocyte function, with impairment of metabolism and regenerative capacity. Several models that duplicate liver functions in vitro are essential tools for studying drug metabolism, liver diseases, and organ regeneration. The human HepaRG cell...

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Detalles Bibliográficos
Autores principales: Bellanti, Francesco, di Bello, Giorgia, Tamborra, Rosanna, Amatruda, Marco, Lo Buglio, Aurelio, Dobrakowski, Michał, Kasperczyk, Aleksandra, Kasperczyk, Sławomir, Serviddio, Gaetano, Vendemiale, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567448/
https://www.ncbi.nlm.nih.gov/pubmed/34786160
http://dx.doi.org/10.4252/wjsc.v13.i10.1595