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PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy

BACKGROUND: Diabetic patients are more vulnerable to skeletal complications. Peroxisome proliferators-activated receptor (PPAR) β/δ has a positive regulatory effect on bone turnover under physiologic glucose concentration; however, the regulatory effect in diabetes mellitus has not been investigated...

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Detalles Bibliográficos
Autores principales: Chen, Miao, Jing, Dian, Ye, Rui, Yi, Jianru, Zhao, Zhihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567548/
https://www.ncbi.nlm.nih.gov/pubmed/34736532
http://dx.doi.org/10.1186/s13287-021-02628-8