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PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy
BACKGROUND: Diabetic patients are more vulnerable to skeletal complications. Peroxisome proliferators-activated receptor (PPAR) β/δ has a positive regulatory effect on bone turnover under physiologic glucose concentration; however, the regulatory effect in diabetes mellitus has not been investigated...
Autores principales: | Chen, Miao, Jing, Dian, Ye, Rui, Yi, Jianru, Zhao, Zhihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567548/ https://www.ncbi.nlm.nih.gov/pubmed/34736532 http://dx.doi.org/10.1186/s13287-021-02628-8 |
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