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Weighted gene co-expression network-based approach to identify key genes associated with anthracycline-induced cardiotoxicity and construction of miRNA-transcription factor-gene regulatory network

BACKGROUND: Cardiotoxicity is a common complication following anthracycline chemotherapy and represents one of the serious adverse reactions affecting life, which severely limits the effective use of anthracyclines in cancer therapy. Although some genes have been investigated by individual studies,...

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Detalles Bibliográficos
Autores principales: Wan, Guoxing, Chen, Peinan, Sun, Xue, Cai, Xiaojun, Yu, Xiongjie, Wang, Xianhe, Cao, Fengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567557/
https://www.ncbi.nlm.nih.gov/pubmed/34732131
http://dx.doi.org/10.1186/s10020-021-00399-9