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Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial

Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these changes. This planned interim analysis reports the gastrointestinal and genitourinary toxicity...

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Detalles Bibliográficos
Autores principales: Kim, Julian O., McDonald, Megan O., Ong, Aldrich, Koul, Rashmi, Dubey, Arbind, Hunter, William, Ahmed, Shahida, Quon, Harvey, Yee, Don, Parliament, Matthew, Sivananthan, Gokulan, Danielson, Brita, Rowe, Lindsay, Ghosh, Sunita, Usmani, Nawaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567697/
https://www.ncbi.nlm.nih.gov/pubmed/34736499
http://dx.doi.org/10.1186/s13014-021-01935-x