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Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial
Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these changes. This planned interim analysis reports the gastrointestinal and genitourinary toxicity...
Autores principales: | Kim, Julian O., McDonald, Megan O., Ong, Aldrich, Koul, Rashmi, Dubey, Arbind, Hunter, William, Ahmed, Shahida, Quon, Harvey, Yee, Don, Parliament, Matthew, Sivananthan, Gokulan, Danielson, Brita, Rowe, Lindsay, Ghosh, Sunita, Usmani, Nawaid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567697/ https://www.ncbi.nlm.nih.gov/pubmed/34736499 http://dx.doi.org/10.1186/s13014-021-01935-x |
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