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Identification of a DNA Methylation-Driven Genes-Based Prognostic Model and Drug Targets in Breast Cancer: In silico Screening of Therapeutic Compounds and in vitro Characterization

DNA methylation is a vital epigenetic change that regulates gene transcription and helps to keep the genome stable. The deregulation hallmark of human cancer is often defined by aberrant DNA methylation which is critical for tumor formation and controls the expression of several tumor-associated gen...

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Detalles Bibliográficos
Autores principales: Tian, Saisai, Fu, Lu, Zhang, Jinbo, Xu, Jia, Yuan, Li, Qin, Jiangjiang, Zhang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567755/
https://www.ncbi.nlm.nih.gov/pubmed/34745136
http://dx.doi.org/10.3389/fimmu.2021.761326