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Spironolactone hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism: in silico studies, statistical optimization, ex vivo, and in vivo studies

Spironolactone (SP) is a potassium sparing diuretic with antiandrogenic properties. This study aimed at formulating SP into hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism. HAECs were prepared by ethanol injection method, according to D-optimal design, after a proper i...

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Detalles Bibliográficos
Autores principales: Albash, Rofida, Fahmy, Abdurrahman M., Hamed, Mohammed I.A., Darwish, Khaled M., El-Dahmy, Rania Moataz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567875/
https://www.ncbi.nlm.nih.gov/pubmed/34726545
http://dx.doi.org/10.1080/10717544.2021.1989089