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Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions

Tobacco use disorder continues to be a leading public health issue and cause of premature death in the United States. Nicotine is considered as the major tobacco alkaloid causing addiction through its actions on nicotinic acetylcholine receptors (nAChRs). Current pharmacotherapies targeting nicotine...

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Detalles Bibliográficos
Autores principales: Tan, Xiaoying, Vrana, Kent, Ding, Zheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568040/
https://www.ncbi.nlm.nih.gov/pubmed/34744656
http://dx.doi.org/10.3389/fnbeh.2021.758252