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Aggregation-Prone Structural Ensembles of Transthyretin Collected With Regression Analysis for NMR Chemical Shift

Monomer dissociation and subsequent misfolding of the transthyretin (TTR) is one of the most critical causative factors of TTR amyloidosis. TTR amyloidosis causes several human diseases, such as senile systemic amyloidosis and familial amyloid cardiomyopathy/polyneuropathy; therefore, it is importan...

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Detalles Bibliográficos
Autores principales: Yang, Wonjin, Kim, Beom Soo, Muniyappan, Srinivasan, Lee, Young-Ho, Kim, Jin Hae, Yu, Wookyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568061/
https://www.ncbi.nlm.nih.gov/pubmed/34746240
http://dx.doi.org/10.3389/fmolb.2021.766830