Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections

To minimize the intrinsic toxicity of the antibacterial agent hydrazinyloxadiazole 1, the hydrazine moiety was replaced with ethylenediamine (compound 7). This replacement generated a potent antifungal agent with no antibacterial activity. Notably, use of a 1,2-diaminocyclohexane moiety, as a confor...

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Detalles Bibliográficos
Autores principales: Hagras, Mohamed, Abutaleb, Nader S., Sayed, Ahmed M., Salama, Ehab A., Seleem, Mohamed N., Mayhoub, Abdelrahman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568133/
https://www.ncbi.nlm.nih.gov/pubmed/34735467
http://dx.doi.org/10.1371/journal.pone.0258465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568133/
https://www.ncbi.nlm.nih.gov/pubmed/34735467
http://dx.doi.org/10.1371/journal.pone.0258465

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