Computational and structural based approach to identify malignant nonsynonymous single nucleotide polymorphisms associated with CDK4 gene

Cycline-dependent kinase 4 (CDK4), an enzyme of the cycline dependent or Ser/Thr protein kinase family, plays a role in cell cycle progression (G1 phase) by phosphorylating a tumor suppressor protein called pRB. Alteration of this enzyme due to missense mutation/ nonsynonymous single nucleotide poly...

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Detalles Bibliográficos
Autores principales: Islam, Rahatul, Rahaman, Mashiur, Hoque, Hammadul, Hasan, Nazmul, Prodhan, Shamsul H., Ruhama, Asfia, Jewel, Nurnabi Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568134/
https://www.ncbi.nlm.nih.gov/pubmed/34735543
http://dx.doi.org/10.1371/journal.pone.0259691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568134/
https://www.ncbi.nlm.nih.gov/pubmed/34735543
http://dx.doi.org/10.1371/journal.pone.0259691

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