Cargando…
Protein conformational transitions explored by a morphing approach based on normal mode analysis in internal coordinates
Large-scale conformational changes are essential for proteins to function properly. Given that these transition events rarely occur, however, it is challenging to comprehend their underlying mechanisms through experimental and theoretical approaches. In this study, we propose a new computational met...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568156/ https://www.ncbi.nlm.nih.gov/pubmed/34735476 http://dx.doi.org/10.1371/journal.pone.0258818 |