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M-DATA: A statistical approach to jointly analyzing de novo mutations for multiple traits
Recent studies have demonstrated that multiple early-onset diseases have shared risk genes, based on findings from de novo mutations (DNMs). Therefore, we may leverage information from one trait to improve statistical power to identify genes for another trait. However, there are few methods that can...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568192/ https://www.ncbi.nlm.nih.gov/pubmed/34735430 http://dx.doi.org/10.1371/journal.pgen.1009849 |