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Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form

The Ebola virus matrix protein VP40 forms distinct structures linked to distinct functions in the virus life cycle. Dimeric VP40 is a structural protein associated with virus assembly, while octameric, ring-shaped VP40 is associated with transcriptional control. In this study, we show that suitable...

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Detalles Bibliográficos
Autores principales: Landeras-Bueno, Sara, Wasserman, Hal, Oliveira, Glenn, VanAernum, Zachary L., Busch, Florian, Salie, Zhe Li, Wysocki, Vicki H., Andersen, Kristian, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568338/
https://www.ncbi.nlm.nih.gov/pubmed/33852858
http://dx.doi.org/10.1016/j.celrep.2021.108986