Anxiety enhances pain in a model of osteoarthritis and is associated with altered endogenous opioid function and reduced opioid analgesia

INTRODUCTION: Negative affect, including anxiety and depression, is prevalent in chronic pain states such as osteoarthritis (OA) and associated with greater use of opioid analgesics, potentially contributing to present and future opioid crises. OBJECTIVES: We tested the hypothesis that the interacti...

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Detalles Bibliográficos
Autores principales: Lillywhite, Amanda, Woodhams, Stephen G., Gonçalves, Sara V., Watson, David J.G., Li, Li, Burston, James J., Gowler, Peter R.W., Canals, Meritxell, Walsh, David A., Hathway, Gareth J., Chapman, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568395/
https://www.ncbi.nlm.nih.gov/pubmed/35128295
http://dx.doi.org/10.1097/PR9.0000000000000956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568395/
https://www.ncbi.nlm.nih.gov/pubmed/35128295
http://dx.doi.org/10.1097/PR9.0000000000000956

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