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Using Immunohistochemistry to Expand the Spectrum of Lynch Syndrome–Related Tumors
The most common genetic and molecular process leading to sporadic colorectal cancer is chromosomal instability. By contrast, mismatch repair deficiency, which results in high levels of microsatellite instability or lack of mismatch repair (MMR) protein expression on immunohistochemistry (IHC), is th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568428/ https://www.ncbi.nlm.nih.gov/pubmed/34746328 http://dx.doi.org/10.14309/crj.0000000000000691 |