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Using Immunohistochemistry to Expand the Spectrum of Lynch Syndrome–Related Tumors

The most common genetic and molecular process leading to sporadic colorectal cancer is chromosomal instability. By contrast, mismatch repair deficiency, which results in high levels of microsatellite instability or lack of mismatch repair (MMR) protein expression on immunohistochemistry (IHC), is th...

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Detalles Bibliográficos
Autores principales: Farha, Natalie, Savage, Erica, Sleiman, Joseph, Burke, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568428/
https://www.ncbi.nlm.nih.gov/pubmed/34746328
http://dx.doi.org/10.14309/crj.0000000000000691