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Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation

Abnormal vascular smooth muscle cell (VSMC) proliferation has an important role in the pathogenesis of both atherosclerosis restenosis and hypertension. Vascular endothelial growth factor (VEGF) has been shown to stimulate VSMC proliferation. In addition, angiogenesis is one of the hallmarks of canc...

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Detalles Bibliográficos
Autores principales: Ran, Feng, Li, Wendong, Qin, Yi, Yu, Tong, Liu, Zhao, Zhou, Min, Liu, Cheng, Qiao, Tong, Li, Xiaoqiang, Yousef, Reda G., Eissa, Ibrahim H., Khalifa, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568530/
https://www.ncbi.nlm.nih.gov/pubmed/34745424
http://dx.doi.org/10.1155/2021/8321400