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Direct modulation of hepatocyte hepcidin signaling by iron

BACKGROUND: Liver-secreted hepcidin is the systemic master switch of iron homeostasis and decreased levels of hepcidin are considered to cause iron overload not only in hereditary hemochromatosis but also in hemolytic anemia and chronic liver diseases. The regulation of hepcidin is complex and its r...

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Detalles Bibliográficos
Autores principales: Yu, Lin-Na, Wang, Shi-Jin, Chen, Cheng, Rausch, Vanessa, Elshaarawy, Omar, Mueller, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568584/
https://www.ncbi.nlm.nih.gov/pubmed/34786173
http://dx.doi.org/10.4254/wjh.v13.i10.1378