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Cleavage-embryo genes and transposable elements are regulated by histone variant H2A.X

During mammalian preimplantation development, stimulation of zygotic genome activation (ZGA) and transposable elements (TEs) shapes totipotency profiling. A rare mouse embryonic stem cells (mESCs) subpopulation is capable of transiently entering a state resembling 2-cell stage embryos, with subtypes...

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Detalles Bibliográficos
Autores principales: SUN, Kai-yi, GUO, Shi-meng, CHENG, Gui-ping, YIN, Ying, HE, Ximiao, ZHOU, Li-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568613/
https://www.ncbi.nlm.nih.gov/pubmed/34393157
http://dx.doi.org/10.1262/jrd.2021-065