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Estrogen‐Induced hsa‐miR‐10b‐5p Is Elevated in T Cells From Patients With Systemic Lupus Erythematosus and Down‐Regulates Serine/Arginine‐Rich Splicing Factor 1

OBJECTIVE: Autoimmune diseases affect women disproportionately more than men. Estrogen is implicated in immune cell dysfunction, yet its precise molecular roles are not fully known. We recently identified new roles for serine/arginine‐rich splicing factor 1 (SRSF1) in T cell function and autoimmunit...

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Detalles Bibliográficos
Autores principales: Ramanujan, Suruchi A., Cravens, Elena N., Krishfield, Suzanne M., Kyttaris, Vasileios C., Moulton, Vaishali R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568617/
https://www.ncbi.nlm.nih.gov/pubmed/33982889
http://dx.doi.org/10.1002/art.41787