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Systematic Combination of Oligonucleotides and Synthetic Polymers for Advanced Therapeutic Applications
The potential of oligonucleotides is exceptional in therapeutics because of their high safety, potency, and specificity compared to conventional therapeutic agents. However, many obstacles, such as low in vivo stability and poor cellular uptake, have hampered their clinical success. Use of polymeric...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Polymer Society of Korea
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568687/ https://www.ncbi.nlm.nih.gov/pubmed/34754286 http://dx.doi.org/10.1007/s13233-021-9093-5 |