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Atherothrombosis model by silencing of protein C in APOE*3-Leiden.CETP transgenic mice

Murine atherosclerosis models are key for investigation of atherosclerosis pathophysiology and drug development. However, they do not feature spontaneous atherothrombosis as a final stage of atherosclerosis. Transgenic mice expressing both the human mutant apolipoprotein E form APOE*3-Leiden and hum...

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Detalles Bibliográficos
Autores principales: Jongejan, Yvonne K., Eikenboom, Jeroen C. J., Gijbels, Marion J. J., Berbée, Jimmy F. P., van Vlijmen, Bart J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568858/
https://www.ncbi.nlm.nih.gov/pubmed/34052976
http://dx.doi.org/10.1007/s11239-021-02488-2