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Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger

Cyclic-oligonucleotide-based antiphage signaling systems (CBASS) are diverse and abundant in bacteria. Here, we present the biochemical and structural characterization of two CBASS systems, composed of CdnG and Cap5, from Asticcacaulis sp. and Lactococcus lactis. We show that CdnG from Asticcacaulis...

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Detalles Bibliográficos
Autores principales: Fatma, Shirin, Chakravarti, Arpita, Zeng, Xuankun, Huang, Raven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568899/
https://www.ncbi.nlm.nih.gov/pubmed/34737303
http://dx.doi.org/10.1038/s41467-021-26738-2