REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expression

Low-dose metronomic chemotherapy (LDMC) inhibits tumor angiogenesis and growth by targeting tumor-associated endothelial cells, but the molecular mechanism has not been fully elucidated. Here, we examined the functional role of regulated in development and DNA damage responses 1 (REDD1), an inhibito...

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Detalles Bibliográficos
Autores principales: Park, Minsik, Kim, Joohwan, Kim, Taesam, Kim, Suji, Park, Wonjin, Ha, Kwon-Soo, Cho, Sung Hwan, Won, Moo-Ho, Lee, Jeong-Hyung, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568908/
https://www.ncbi.nlm.nih.gov/pubmed/34697389
http://dx.doi.org/10.1038/s12276-021-00690-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568908/
https://www.ncbi.nlm.nih.gov/pubmed/34697389
http://dx.doi.org/10.1038/s12276-021-00690-z

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