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Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases

IKKα and IKKβ are essential kinases for activating NF-κB transcription factors that regulate cellular differentiation and inflammation. By virtue of their small size, chemokines support the crosstalk between cartilage and other joint compartments and contribute to immune cell chemotaxis in osteoarth...

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Detalles Bibliográficos
Autores principales: Olivotto, Eleonora, Minguzzi, Manuela, D’Adamo, Stefania, Astolfi, Annalisa, Santi, Spartaco, Uguccioni, Mariagrazia, Marcu, Kenneth B., Borzì, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568921/
https://www.ncbi.nlm.nih.gov/pubmed/34737366
http://dx.doi.org/10.1038/s41598-021-01063-2