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Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases
IKKα and IKKβ are essential kinases for activating NF-κB transcription factors that regulate cellular differentiation and inflammation. By virtue of their small size, chemokines support the crosstalk between cartilage and other joint compartments and contribute to immune cell chemotaxis in osteoarth...
Autores principales: | Olivotto, Eleonora, Minguzzi, Manuela, D’Adamo, Stefania, Astolfi, Annalisa, Santi, Spartaco, Uguccioni, Mariagrazia, Marcu, Kenneth B., Borzì, Rosa Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568921/ https://www.ncbi.nlm.nih.gov/pubmed/34737366 http://dx.doi.org/10.1038/s41598-021-01063-2 |
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