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Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine

Small intestine neuroendocrine tumor (SI-NET), the most common cancer of the small bowel, often displays a curious multifocal phenotype with several tumors clustered together in a limited intestinal segment. SI-NET also shows an unusual absence of driver mutations explaining tumor initiation and met...

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Detalles Bibliográficos
Autores principales: Elias, Erik, Ardalan, Arman, Lindberg, Markus, Reinsbach, Susanne E., Muth, Andreas, Nilsson, Ola, Arvidsson, Yvonne, Larsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568927/
https://www.ncbi.nlm.nih.gov/pubmed/34737276
http://dx.doi.org/10.1038/s41467-021-26581-5