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An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

Chronic Obstructive Pulmonary Disease is a generally smoking-linked major cause of morbidity and mortality. Genome-wide Association Studies identified a locus including a non-synonymous single nucleotide polymorphism in CHRNA5, rs16969968, encoding the nicotinic acetylcholine receptor α5 subunit, pr...

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Detalles Bibliográficos
Autores principales: Routhier, Julie, Pons, Stéphanie, Freidja, Mohamed Lamine, Dalstein, Véronique, Cutrona, Jérôme, Jonquet, Antoine, Lalun, Nathalie, Mérol, Jean-Claude, Lathrop, Mark, Stitzel, Jerry A., Kervoaze, Gwenola, Pichavant, Muriel, Gosset, Philippe, Tournier, Jean-Marie, Birembaut, Philippe, Dormoy, Valérian, Maskos, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568944/
https://www.ncbi.nlm.nih.gov/pubmed/34737286
http://dx.doi.org/10.1038/s41467-021-26637-6