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Site-Specific Protein Modifications by an Engineered Asparaginyl Endopeptidase from Viola canadensis

Asparaginyl endopeptidases (AEPs) or legumains are Asn/Asp (Asx)-specific proteases that break peptide bonds, but also function as peptide asparaginyl ligases (PALs) that make peptide bonds. This ligase activity can be used for site-specific protein modifications in biochemical and biotechnological...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Zhang, Dingpeng, Zhang, Xiaohong, Wang, Zhen, Liu, Chuan-Fa, Tam, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568951/
https://www.ncbi.nlm.nih.gov/pubmed/34746098
http://dx.doi.org/10.3389/fchem.2021.768854