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Site-Specific Protein Modifications by an Engineered Asparaginyl Endopeptidase from Viola canadensis
Asparaginyl endopeptidases (AEPs) or legumains are Asn/Asp (Asx)-specific proteases that break peptide bonds, but also function as peptide asparaginyl ligases (PALs) that make peptide bonds. This ligase activity can be used for site-specific protein modifications in biochemical and biotechnological...
Autores principales: | Chen, Yu, Zhang, Dingpeng, Zhang, Xiaohong, Wang, Zhen, Liu, Chuan-Fa, Tam, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568951/ https://www.ncbi.nlm.nih.gov/pubmed/34746098 http://dx.doi.org/10.3389/fchem.2021.768854 |
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